Publications

2026

The glucose uptake inhibitor SgrS is induced by D-serine yet does not contribute to growth arrest in enterohaemorrhagic Escherichia coli

Catabolism of serine enantiomers represses enterohemorrhagic Escherichia coli virulence factors via modulation of the nitrogen stress response

2024

Aurodox inhibits type III secretion in multiple Gram-negative pathogens

A master regulator of central carbon metabolism directly activates virulence gene expression in attaching and effacing pathogens

Aurodox, a polyketide from Streptomyces goldiniensis, inhibits transcription of the type III secretion system of multiple Gram-negative pathogens

2023

Enhancing a multi-purpose artificial urine for culture and gene expression studies of uropathogenic Escherichia coli strains

D-Serine reduces the expression of the cytopathic genotoxin colibactin

Distinct ecological fitness factors coordinated by a conserved Escherichia coli regulator during systemic bloodstream infection

2022

Distinct ecological fitness factors coordinated by a conserved Escherichia coli regulator during systemic bloodstream infection

Control of resistance against bacteriophage killing by a metabolic regulator in meningitis-associated Escherichia coli

Validation of a random Vibrio parahaemolyticus genomic library by selection of quinolone resistance in a heterologous host

2021

D-Serine induces distinct transcriptomes in diverse Escherichia coli pathotypes

2020

A highly conserved complete accessory Escherichia coli type III secretion system 2 is widespread in bloodstream isolates of the ST69 lineage

Prokaryotic life finds a way: insights from evolutionary experimentation in bacteria

The force awakens: The dark side of mechanosensing in bacterial pathogens

Heterogeneity in populations of enterohaemorrhagic Escherichia coli undergoing D-serine adaptation

Differentiated ovine tracheal epithelial cells support the colonisation of pathogenic and non-pathogenic strains of Mannheimia haemolytica

Genomic plasticity of pathogenic Escherichia coli mediates d-serine tolerance via multiple adaptive mechanisms

Widespread Strain-Specific Distinctions in Chromosomal Binding Dynamics of a Highly Conserved Escherichia coli Transcription Factor

Plastic Circuits: Regulatory Flexibility in Fine Tuning Pathogen Success

2019

Distinct intraspecies virulence mechanisms regulated by a conserved transcription factor

2018

Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion

Characterization of the Mode of Action of Aurodox, a Type III Secretion System Inhibitor from Streptomyces goldiniensis

Optimisation of growth conditions for ovine airway epithelial cell differentiation at an air-liquid interface

Tracking elusive cargo: Illuminating spatio-temporal Type 3 effector protein dynamics using reporters

2017

Temporal dynamics of ovine airway epithelial cell differentiation at an air-liquid interface

2014

Manipulation of intestinal epithelial cell function by the cell contact-dependent type III secretion systems of Vibrio parahaemolyticus

2013

The MSHA pilus of Vibrio parahaemolyticus has lectin functionality and enables TTSS-mediated pathogenicity